Feline Arterial Thromboembolism

According to Smith & Tobias (JVIM 2004), which of the following statements about feline arterial thromboembolism (ATE) is CORRECT?

Rectal temperature higher than 37.1 C° will correctly identify 3/4 of survivors

Blood glucose concentration is directly associated with clinical outcome

Tachycardia is associated with the severity of arterial obstruction

Hypothermia lasting for more than three days is associated with a poor clinical outcome.

Which of the following statements about feline arterial thromboembolism (ATE) is CORRECT?

ATE is always accompanied by acute and painful hind limb paresis (or paralysis).

Resting glucose value below 2.5 mmol/l is almost pathognomonic of ATE.

Rectal temperature at presentation is the most reliable prognostic value.

ATE is always associated with a severe left atrial dilation.

What is the main outcome of the FAT CAT study?

Clopidogrel administration was associated with significantly reduced likelihood of recurrent ATE compared to aspirin

Clopidogrel was associated with a significantly increased likelihood of cardiac death

Unlike aspirin, clopidogrel administration was well tolerated in all cats.

Clopidogrel caused significant haemorrhage in some cats.

Which of the following clinical signs is not typically present in FATE?

Absence of femoral pulses

Hyperthermia

Pain

Tachypnoea

Which of the following serum biochemistry is more specific for skeletal muscle damage?

Troponin-I

ALT

CK

Glucose

According to Smith’s study, what is the recurrence rate of ATE?

17%

27%

37%

47%

What is the approximate percent survival in cats who survive the first 24 following an ATE event?

30%

50%

70%

90%

Which of the following drugs is currently under evaluation in the SUPERCAT Study?

Aspirin

Warfarin

Sildenafil

Rivaroxaban

What is the pharmacological function of clopidogrel

Factor X inhibitor

Factor IX inhibitor

Factor V inhibitor

ADP receptor inhibitor

What is the rationale of using a low-dose aspirin (i.e. 5mg/cat q72h)?

Reducing the inhibition of prostaglandins

Reducing the inhibition of thromboxane

Increasing the inhibition of factor X

Increasing the inhibition of factor V

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Feline Arterial Thromboembolism