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Toxicology – Treatment and management of paracetamol and recreational drugs

  • VET WEBINAR
  • Toxicology – Treatment and management of paracetamol and recreational drugs
Lädt!
Which statement regarding paracetamol is true?
It can be safely used in cats at a low dose
Dogs commonly show overt signs of methaemoglobinaemia
In cats, liver failure is the first signs
It causes chocolate-coloured discolouration of the blood
 
NSAIDS do not cause
GI injury
Methaemoglobinaemia
Renal failure
Seizures
 
Synthetic cannabinoids
Are not toxic to dogs
Are indistinguishable from natural cannabis in their toxidrome
Cause more severe signs than natural cannabis
Are usually fatal to dogs
 
Amphetamines cause
Tachycardia and hypertension
Urinary incontinence
Depression to coma
No major clinical signs
 
Which combination of species and appropriate emetic agent is correct
Dog, washing soda powder
Cat, washing soda crystal
Dog, medetomidine
Cat, dexmedetomidine
 
Activated charcoal
Should be given to all toxicosis cases
Should always be given in combination with sorbitol
Works by accelerating urinary elimination
Works by adsorbing toxins in the GIT
 
Which type of extracorporeal therapy is correctly matched to the type of molecule it can remove
Haemodialysis – small and non-protein bound
Plasmapheresis – non-protein bound and large volume of distribution
Charcoal haemoperfusion – heavy metals
Plateletpheresis – protein bound plasma molecules
 
Intravenous lipid emulsion may be useful for
Lipid soluble toxins, ie those with a low LogD
Lipid soluble toxins, ie those with a high LogD
Lipid insoluble toxins, ie those with a low LogD
Lipid insoluble toxins, ie those with a high LogD
 
Which toxin is matched with a supportive treatment that is often necessary
Paracetamol – alpha and beta adrenergic antagonists
Paracetamol – PPIs and antiemetics
Amphetamines – alpha and beta adrenergic antagonists
Amphetamines – PPIs and antiemetics
 
What is the antidote for paracetamol?
Misoprostol
Dexmedetomidine
Naloxone
N-acetylcysteine