I think the dog has bone cancer. What's next?

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  • I think the dog has bone cancer. What's next?
Lädt!
A dog with appendicular osteosarcoma was treated with amputation and chemotherapy. Follow-up thoracic x-rays revealed several pulmonary nodules consistent with pulmonary metastasis. What is the treatment of choice?
Pulmonary metastasectomy.
Palladia®.
More chemotherapy.
None of the above.
 
How accurate is cytology in obtaining a diagnosis of specific tumour subtype (e.g. sarcoma, carcinoma)?
Not accurate. All suspect bone lesions require a bone biopsy.
Not accurate. 39-43%.
Fairly accurate. 69-83%.
100% accurate with proper cytologic technique.
 
What is the prognosis for dogs with nonmetastatic appendicular osteosarcoma following amputation and chemotherapy?
Guarded. Most dogs will die or be humanely euthanised within a few months.
Poor. The median survival time is 4 to 5 months, with a 1-year survival rate of 10%.
Fair. The median survival time is 10 to 12 months, with a 2-year survival rate of 20%.
Fair. The median survival time is 9.6 months to 1.1 years.
 
Which of the following is considered a FAVOURABLE prognostic factor for dogs with appendicular osteosarcoma?
Elevated serum alkaline phosphatase.
Proximal humerus location.
Circulating monocyte counts >0.4 and lymphocyte counts >1.0.
Ulna location.
 
What is the median survival time for dogs with appendicular osteosarcoma and confirmed nodal metastasis that undergoes amputation?
3 weeks.
2 months.
4 months.
5 months.
 
How well do dogs with nonmetastatic appendicular osteosarcoma do with stereotactic radiation therapy and chemotherapy?
They have a similar survival time to dogs treated with amputation followed by chemotherapy.
They have a similar survival time to dogs treated with amputation alone.
They do worse than dogs that undergo amputation followed by chemotherapy.
They do worse than dogs that undergo amputation alone.
 
Which of the following is the best test for the detection of bone metastasis?
Plain bone survey radiographs of all bones and pelvis.
Whole-body CT.
Bone scintigraphy.
MRI.
 
What is the standard of care staging tests, that should be performed in all dogs with suspected or confirmed appendicular osteosarcoma before surgery?
Haematology, serum biochemistry and three-view thoracic radiographs.
Haematology, serum biochemistry and thoracic CT.
Haematology, serum biochemistry, three-view thoracic radiographs, and plain bone survey radiographs.
Haematology, serum biochemistry, thoracic CT and bone scintigraphy.
 
What does osteosarcoma typically look like on x-rays?
Codman’s triangle, cortical lysis, lesion in mid diaphysis, do not cross joint space.
Codman’s triangle, cortical lysis, lesion in mid diaphysis, crosses the joint space.
Codman’s triangle, cortical lysis, lesion in metaphysis, do not cross joint space.
Codman’s triangle, cortical lysis, lesion in metaphysis, crosses the joint space.
 
What is the chance of finding abdominal metastasis in dogs with appendicular osteosarcoma?
0%.
2.5%.
10%.
25%.