The Hyperthyroid Cat

cTSH measurement (canine) is not used to diagnose feline hyperthyroidism because:

Normal cats often have cTSH below the limit of assay detection

It can be used but not in cats with apathetic hyperthyroidism

Hyperthyroid cats have high cTSH

Hyperthyroid cats have reference range cTSH

Free T4 measurement confirms hyperthyroidism in which situation?

Lower end reference range TT4 and high free T4

High TT4 and lower end reference range free T4

Below reference range TT4 and high free T4

Mid-upper reference range TT4 and high free T4

Methimazole side effects include which one of the following?

Acute kidney injury secondary to direct nephrotoxicity

Thrombocytopenia secondary to bone marrow suppression

Seizures secondary to reduced heart rate and brain hypoxia

Weakness secondary to an immune mediated myopathy

Which of the following antithyroid drug side effects may not require complete cessation of treatment?

Hepatotoxicity

Gastrointestinal signs

Bone marrow suppression

Cutaneous drug reaction

Thyroid scintigraphy can be used to:

Definitively diagnose carcinoma in the absence of metastases

Diagnose hypothyroidism

Assess treatment response to methimazole

Determine disease control with an iodine restricted diet

In relation to goitres in hyperthyroid cats:

Approximately ¼ will have functional ectopic tissue

70% have unilateral goitres

Goitre palpation can usually differentiate carcinoma from hyperplasia

Goitres are always functional

A diagnosis of hypothyroidism is confirmed by identifying:

Low TT4, low free T4 and high TSH

Low TT4, low free T4 and low TSH

Low TT4, high free T4 and low TSH

Normal TT4, normal free T4 and normal TSH

Left untreated, persistent hypothyroidism leads to:

Reduced GFR and progressive CKD

Increased GFR and progressive CKD

Normal GFR and progressive CKD

Low GFR and acute kidney injury

The cardiac biomarker NT-proBNP:

Is increased in cats with primary HCM and hyperthyroidism

Can differentiate primary HCM and hyperthyroidism pre-treatment

Stays increased after curative treatment of cats with hyperthyroidism alone

Reduces over time in cats with primary HCM

Which of the following is not a clinical sign of hypothyroidism in cats?

Lethargy

Weight gain

Hypothermia

Truncal alopecia

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The Hyperthyroid Cat